Built around the middle of the 15th century, it is a remarkable example of late Gothic-Renaissance art. Commissioned by Simone Caccetta, who did not dedicate himself exclusively to commerce: already procurator of the Palagano family, he held various positions, reaching his peak with his appointment, in 1449, as master portolano for Puglia and Capitanata. Acquired by the municipality in 1484, it was the residence of the Venetian governors and it was from here that news of the Italian victory in the Challenge of Barletta, fought in the countryside of Trani, spread. In the 17th century, it became the convent of the Discalced Carmelites. The palace underwent numerous alterations until the end of the 19th century. The imposing entrance features an ogival arch framed by acanthus leaves. The triple lancet window preserves intact the side brackets originally intended for drapery, and influences of Venetian art can be perceived in its decoration.