Built in 1755 by Geronimo Palumbo, the palace represents the most significant example of Baroque civil architecture in the city. Although the family was always present in the city, it is believed that Geronimo came from a family in Cerignola. He was an influential merchant and exporter of grain. The family had its own tomb in the church of San Domenico, in the area that once belonged to the De Angelis. In 1806, the palace became the home of Baron Riccardo Candido. In 1872, it was acquired by the Quercia and Brunetti families. Adolfo Quercia, to whom the adjacent square is dedicated, was mayor of Trani in the early 20th century. Later, the large flat on the main façade passed to the Campione family, who are still its custodians today. The fresco on the monumental staircase, by Thomas Fontana, stands out.